Buscopan Venus Special Precautions

In case severe, unexplained abdominal pain persists or worsens, or occurs together with symptoms like fever, nausea, vomiting, changes in bowel movements, abdominal tenderness, decreased blood pressure, fainting or blood in stool, medical advice should immediately be sought. To prevent overdosing, it should be ensured that any other drugs taken concurrently do not contain paracetamol, one of the active components of Hyoscine-N-butylbromide + Paracetamol (Buscopan Venus). Liver damage may result if the recommended dosage for paracetamol is exceeded.
Hyoscine-N-butylbromide + Paracetamol (Buscopan Venus) should be used with caution in: glucose-6-phosphate-dehydrogenase deficiency, hepatic dysfunction (e.g. due to chronic alcohol abuse, hepatitis), impaired renal function, Gilbert's syndrome, and hepatocellular insufficiency (Child-Pugh A/B).
In such cases Hyoscine-N-butylbromide + Paracetamol (Buscopan Venus) should only be used under medical supervision and, if necessary, the dose reduced or the intervals between the individual administrations prolonged. The blood count and renal and liver function should be monitored after prolonged use.
Extensive use of analgesics, especially at high doses, may induce headaches that must not be treated with increased doses of the drug.
Severe acute hypersensitivity reactions (e.g. anaphylactic shock) are very infrequently observed. Treatment must be discontinued at the first signs of a hypersensitivity reaction following the administration of Hyoscine-N-butylbromide + Paracetamol (Buscopan Venus).
Abrupt discontinuation of analgesic after prolonged use at high doses may induce withdrawal symptoms (e.g. headache, tiredness, nervousness), that typically resolve within few days. Reintake of analgesics should depend upon physician's advice, and withdrawal symptoms abated.
Hyoscine-N-butylbromide + Paracetamol (Buscopan Venus) should not be taken for more than 3 days unless directed by a physician. The patient should be instructed to seek medical advice, if pain persists or gets worse, if new symptoms occur, or if redness or swelling is present because these could be signs of a serious condition.
Because of the potential risk of anticholinergic complications, caution should be used in patients prone to narrow angle glaucoma as well as in patients susceptible to intestinal or urinary outlet obstructions and in those inclined to tachyarrhythmia.
Hyoscine-N-butylbromide + Paracetamol (Buscopan Venus) tablets contain 4.32 mg of sodium per unit resulting in 25.92 mg sodium per maximum recommended daily dose. To be taken into consideration for patients on a controlled sodium diet.